Publications
*co-first author, ‡corresponding author
Belyaeva J, Elgeti M‡. Exploring protein structural ensembles: Integration of sparse experimental data from electron paramagnetic resonance spectroscopy with molecular modeling methods. (2024). eLife, 13: e99770.
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Zhao J, Elgeti M*‡, O’Brien ES, Sár CP, El Daibani A, Heng J, Sun X, Che T, Hubbell WL, Kobilka BK, Chen C. Ligand efficacy modulates conformational dynamics of the μ-opioid receptor. (2024). Nature, 629: 474-480.
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preprint
Khan F, Elgeti M*‡, Grandfield S, Paz A, Naughton FB, Marcoline FV, Althoff T, Ermolova N, Wright EM, Hubbell WL, Grabe M, Abramson J. Membrane potential accelerates sugar uptake by stabilizing the outward facing conformation of the Na/glucose symporter vSGLT. (2023). Nature Communications, 14: 7511.
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Wygas MM, Laugwitz JM, Schmidt P, Elgeti M, Kaiser A. Dynamics of the Second Extracellular Loop Control Transducer Coupling of Peptide-Activated GPCRs. (2023). International Journal of Molecular Sciences, 24 (15): 12197.
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Elgeti M‡ and Hubbell WL (2021). DEER Analysis of GPCR Conformational Heterogeneity. Biomolecules, 11: 778.
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Lerch MT, Matt RA, Masureel M, Elgeti M, Kumar KK, Hilger D, Foys B, Kobilka BK, Hubbell WL (2020). Viewing Rare Conformations of the β2-Adrenergic Receptor with Pressure-Resolved DEER Spectroscopy. PNAS, 117: 31824–31.
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McMahon C, Staus DP, Wingler LM, Wang J, Skiba MA, Elgeti M, Hubbell WL, Rockman HA, Kruse AC, Lefkowitz RJ (2020). Synthetic Nanobodies as Angiotensin Receptor Blockers. PNAS, 117: 20284–91.
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Hellwig S, Grittner U, Elgeti M, Wyschkon S, Fiebach JB, Krause T, Herm J, Scheitz JF, Endres M, Nolte CH, Haeusler KG, Elgeti T (2020). Evaluation of left ventricular function in patients with acute ischaemic stroke using cine cardiovascular magnetic resonance imaging. ESC Heart Failure, 7: 2572–2580.
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Schaafs LA, Wyschkon S, Elgeti M, Nagel SN, Knebel F, Steffen IG, Makowski MR, Hamm B, Elgeti T (2020). Diagnosis of Left Ventricular Diastolic Dysfunction Using Cardiac Magnetic Resonance Imaging: Comparison of Volume-Time Curves Derived from Long- and Short-Axis Cine Steady-State Free Precession Datasets. Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 192: 764–775.
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Wingler LM, Elgeti M*, Hilger D, Latorraca NR, Lerch MT, Staus DP, Dror RO, Kobilka BK, Hubbell WL, Lefkowitz RJ (2019). Angiotensin Analogs with Divergent Bias Stabilize Distinct Receptor Conformations. Cell 176: 468-78.
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Elgeti M‡, Kazmin R, Rose AS, Szczepek M, Hildebrand PW, Bartl FJ, Scheerer P, Hofmann KP (2018). The Arrestin- 1 Finger Loop Interacts with Two Distinct Conformations of Active Rhodopsin. Journal of Biological Chemistry 293: 4403–10.
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Dacquay Y, Lee JR, Govetto A, Elgeti M, Hubbell WL, Kavehpour P, Hubschman J-P (2016). Condensation on Intraocular Lenses During Vitrectomy: Effect of Perfluorocarbon Liquids. Journal for Modeling in Ophthalmology 1: 71– 79.
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Kazmin R, Rose AS, Szczepek M, Elgeti M, Ritter E, Piechnick R, Hofmann KP, Scheerer P, Hildebrand PW, Bartl FJ (2015). The Activation Pathway of Human Rhodopsin in Comparison to Bovine Rhodopsin. Journal of Biological Chemistry 290: 20117–27.
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Sommer ME, Elgeti M, Hildebrand PW, Szczepek M, Hofmann KP, Scheerer P (2015). Structure-Based Biophysical Analysis of the Interaction of Rhodopsin with G protein and Arrestin. Methods in Enzymology 556: 563–608.
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Szczepek M, Beyrière F, Hofmann KP, Elgeti M, Kazmin R, Rose AS, Bartl FJ, von Stetten D, Heck M, Sommer ME, Hildebrand PW, Scheerer P (2014). Crystal Structure of a Common GPCR-Binding Interface for G protein and Arrestin. Nature Communications 5: 4801.
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Rose AS, Elgeti M, Zachariae U, Grubmüller H, Hofmann KP, Scheerer P, Hildebrand PW (2014). Position of Transmembrane Helix 6 Determines Receptor G protein Coupling Specificity. Journal of the American Chemical Society 136: 11244–7.
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Elgeti M‡, Rose AS, Bartl FJ, Hildebrand PW, Hofmann KP, Heck M (2013). Precision vs Flexibility in GPCR Signaling. Journal of American Chemical Society 135: 12305–12.
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Elgeti M‡, Kazmin R, Heck M, Morizumi T, Ritter E, Scheerer P, Ernst OP, Siebert F, Hofmann KP, Bartl FJ (2011). Conserved Tyr223(5.58) Plays Different Roles in the Activation and G-protein Interaction of Rhodopsin. Journal of the American Chemical Society 133: 7159–65.
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Ritter E, Elgeti M, Bartl FJ (2008). Activity Switches of Rhodopsin. Photochemistry Photobiology 84: 911–20.
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Elgeti M, Ritter E, Bartl FJ (2008). New Insights into Light-Induced Deactivation of Active Rhodopsin by SVD and Global Analysis of Time-Resolved UV/Vis- and FTIR-Data. Zeitschrift für Physikalische Chemie 222: 1117–29.
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Ritter E, Elgeti M*, Hofmann KP, Bartl FJ (2007). Deactivation and Proton Transfer in Light-Induced Metarhodopsin II/Metarhodopsin III Conversion: A Time-Resolved Fourier Transform Infrared Spectroscopic Study. Journal of Biological Chemistry 282: 10720–30.
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